Bed bugs are such a nuisance, right? Imagine buying a bed or a piece of used furniture with your hard-earned money only to find out that they contain bed bugs. In such a scenario, how to kill bed bugs is an essential question that needs to be addressed. There is not much that you can do to kill bed bugs using physical methods. In fact, most cases would require you to kill bed bugs with chemicals.

chemicals which are used in killing bed bugs and their eggs

So, now to the real question:
“What chemicals kill bed bugs and their eggs?” and more importantly, “What chemicals do exterminators use to kill bed bugs?”

Chemicals Used For Killing Bed Bugs

If you had been wondering what chemicals do pest control companies use for bed bugs, then here’s a comprehensive list:

  1. Pyrethrins
  2. Pyrethroids
  3. Desiccants
  4. Biochemicals
  5. Pyrroles
  6. Neonicotinoids
  7. Insect growth regulators

In this article, we would not only go through their action process but also discuss where to buy these chemicals to kill bed bugs.


how to kill bed bugs using pyrethrin

Pyrethrin is amongst the most common chemicals used in insecticides. It is derived from the flowers of the chrysanthemum plant which means that it is natural!

Although bed bugs can obtain immunity against pyrethrin, it is still extremely effective in killing most of their types.

Pyrethrin seeps through the cuticle of the bed bug’s skin and binds to sodium channels on nerve cells. When that happens, bed bugs struggle to conduct nerve impulses normally.

This results in the bed bug sending too many nerve impulses throughout its body which ultimately kills the insect.


  • Obtained through herbal extracts.
  • Major constituent in insecticides and pesticides.


  • Bed bugs can attain immunity against it.
  • It loses its effectiveness within a day.

Where To Buy Pyrethrin?

In case you’ve decided to use this chemical to eradicate bed bugs, here is a great option: The Bonide Pyrethrin Spray Concentrate.

This 8 oz bottle is honestly going to be more than enough for killing bed bugs. The company advises to only use 3 tablespoons of the product in a whole gallon of water!


how to kill bed bugs using pyrethroid

These are the second most common chemicals used in bed bug sprays. These chemicals are synthesized in a lab and are not obtained through natural sources.

Till date, over 1000 types of pyrethroids have been synthesized. In fact, they are even used in shampoos as an anti-lice chemical as well as in products used for killing mosquitos.

As a downside, it is quite common for bed bug colonies and strains to obtain immunity against this chemical.


  • Dozens of options are available in the market.
  • A major constituent of insecticides.


  • Bed bugs can obtain immunity against them.
  • Short lifespan.

Where To Buy Pyrethroids?

Permethrin SFR is an excellent pyrethroid product that can help you get rid of those irritating bed bugs once and for all.

This product has absolutely no odor which makes it easy to use in homes.


how to kill bed bugs using desiccants

Desiccants are somewhat dangerous chemicals that serve to dehydrate the body of a bed bug.

What’s excellent about desiccants is that they, unlike pyrethrin and pyrethroids, have a long-lasting effect on bed bugs.

But beware; desiccants can be extremely dangerous for humans if inhaled in large amounts. Furthermore, you should always ensure that the product that you’re using is approved as an insecticide by relevant authorities.


  • Bed bugs can not obtain immunity against them.
  • Long-lasting effect.


  • Requires consideration to choose a suitable desiccant.
  • Slow action.

Where To Buy Desiccants?

The Cimexa Insecticide Dust is an excellent desiccant that is specially formulated for killing bed bugs. It would get rid of the adult bed bugs as well as the nymphs and eggs that could easily reproduce the community if they aren’t killed on time.

This product is odorless and also does not leave any stains on beds or furniture.

If you’re not up for buying this product, you could invest in a formulation of boric acid which is readily available in the cleaning section of supermarkets as well as in pharmacies.


how to kill bed bugs using biochemicals

As the name suggests, biochemicals are natural bed bug killing chemicals. Neem oil is, by far, the most common biochemical used for killing bed bugs.

Although neem oil sounds like a feasible option, yet it won’t have that much of an effect on bed bugs unless they come in contact with it.

But wait, don’t dismiss this option too soon because here comes the good part: neem oil can help prevent you from being bitten. What’s more, it would provide relief to you as an ointment after you are bitten.


  • Obtained naturally.
  • It can be used as a preventive ointment.


  • Effective for a short period.
  • Only acts on bed bugs when in contact.

Where To Buy Biochemicals?

This organic neem oil is a top-notch option if you’re looking for a cold-pressed neem oil product. It would not only help to kill bed bugs but could also be used for hair and skin nourishment.


how to kill bed bugs using pyrroles

Pyrrole pesticides are another option for combating bed bugs. Although pyrroles themselves are not effective against bed bugs, they are converted into certain products that are.

It is worth noting that pyrroles can only kill the adult bed bugs and not their eggs.

A common example of such a pyrrole is Chlorfenapyr.


  • Highly effective when mixed with other chemicals.


  • It does not kill bed bug eggs.

Where To Buy Pyrroles?

Although pyrroles alone are not enough to combat a bed bug infestation, yet they are beneficial components for products like the Control Solutions SPECTRE 2 SC that contains 21.45% of Chlorfenapyr. The product is almost odorless and is exceptionally long-lasting.


These are prepared in the lab from nicotine which is a chemical found in cigarettes.

The method of action for neonicotinoids is quite similar to pyrethrin as it acts on the nerves to increase the rate of electrical impulses. This eventually leads to the death of bed bugs.

The great thing about neonicotinoids is that bed bugs can not obtain resistance against them.


  • Bed bugs can not obtain resistance against them.


  • Ineffective if used alone.

Where To Buy Neonicotinoids?

As mentioned above, neonicotinoids are usually not used alone. They are found in pesticide products that generally contain other chemicals including pyrethrin and pyrethroids.

Insect Growth Regulators

how to kill bed bugs using insect growth regulators

Out of all the chemicals mentioned above, Insect Growth Regulators (IGRs) might have the most different line of action against bed bugs.

IGRs induce hormones in the body of bed bugs which alter their usual growth rate. They could either speed up the aging process of bed bugs or completely halt it.

It can be beneficial for people who wish to inhibit the bed bugs from growing in number. After this, the use of other chemicals for killing bed bugs would be highly advised.


  • Halts growth of the bed bug population.


  • It does not kill bed bugs.

Where To Buy IGRs?

Like neonicotinoids, IGRs are not used as a lone product for killing bed bugs. They are used along with several other chemicals for better efficacy. In case you are looking for a quality product that contains the right amount of insect growth regulators, then you might want to check out Gentrol Complete IGR Insecticide.

Side Effects Of Bed Bug Chemical Treatment

Dealing with chemicals is never safe.

Many people undergo severe respiratory issues while using or accidentally inhaling these chemicals. These chemicals can harm eyes as well as cause rashes if they come into contact with the skin.

So, how to prevent this outcome? Be sure that you wear protective gear like gloves, masks, and goggles while using these chemicals.


Bed bugs can genuinely make life hard for anyone. Preventing bed bugs from entering your home is the best solution. But if you have a clear line-of-action against them and the knowledge of which chemicals to use for that purpose, then killing them would be no issue for you.